Scientists used a method called magnetic hyperthermia, which caused magnetic particles to heat in the area of tumor tissue and damage the tumor tissue.
With the developing technology, various treatment methods are also being developed experimentally. Now, researchers from University College London have suggested that treatment methods for cancer that contain magnetic nanoparticles, in addition to conventional chemotherapy, will increase the effectiveness of treatment.
For more than 10 years, scientists have been aiming to kill tumor cells by increasing their temperature, thereby ensuring the development of various treatment methods. (Cancer cells are generally much more sensitive to temperature increase than healthy cells.) Normally, human somatic (diploid), any biological cell that forms the body of an organism.Somatic cell, gamete, germ cell, which is related to reproduction in a multicellular organism. It is the name given to all cells other than gametocytes or undifferentiated stem cells.) cells generally survive up to 45 ° C, while tumor cells die around 42 ° C.
Scientists searched for ways to selectively heat cancer cells, and they used a method called magnetic hyperthermia that allows magnetic particles to reach the tumor tissue’s location and heat these particles using magnetic fields, thus allowing the surrounding tissues to die with relatively less damage. In addition, the research team combined this method with traditional chemotherapy.
The developed method was tested on cell lines of various human cancers (prostate, brain and breast) and magnetic particles were filled with the chemotherapeutic agent, doxorubicin. As a result of the studies, it was observed that the new method, in which more cancer cells were damaged in all cell lines compared to chemotherapeutic treatment alone, was 34% more successful than classical chemotherapy.